近日,厦门大学刘文教授团队在《Advanced Science》上发表题为“Estrogen-Induced LncRNA, LINC02568, Promotes Estrogen Receptor-Positive Breast Cancer Development and Drug Resistance Through Both In Trans and In Cis Mechanisms”的研究论文,研究结果揭示了LINC12在调节ER阳性乳腺癌ERα信号传导和pH稳态方面的双重机制,并表明靶向LINC104可能是临床上潜在的治疗途径。